碳酸二甲酯是一种性能优良、绿色环保的有机化学品，是一种转化温室气体CO2的潜在有效途径。其合成与应用在近年来受到了越来越多的专家及学者的关注。 首先，对合成碳酸二甲酯的各个工艺进行了热力学分析，结果表明：二氧化碳和甲醇一步合成工艺在热力学上不可行，加入耦合剂后改变了该过程的反应路径，使其在热力学上可行；对目前酯交换工艺用到的耦合剂进行分析比较后，我们发现以环氧氯丙烷为耦合剂的反应较环氧丙烷在热力学上更为有利；甲醇氧化羰基化工艺作为另一种研究较多的合成DMC工艺，其在热力学上表现出一定的优越性，在低温高压下较为有利。 其次，采用Aspen plus 软件分别对以环氧丙烷、环氧氯丙烷为耦合剂的酯交换工艺及甲醇氧化羰基化工艺流程进行了模拟与优化，具体分析了当前两种工艺存在的主要问题：酯交换工艺副产物多、能耗高；甲醇气相氧化羰基化工艺甲醇单程转化率低、分离困难等。在此基础上，我们提出了一种新的工艺体系—甲醇氧化羰基化-酯交换耦合工艺体系，并对该工艺进行了热力学可行性分析及流程模拟，分析后发现：该耦合工艺的提出使得甲醇转化率大幅提高，一方面可大幅减少甲醇循环量，降低循环能耗，解决酯交换工艺存在的高能耗问题，另一方面降低甲醇/DMC分离难度，可采用一般精馏对二者进行分离；副产物H2O基本完全转化，解决甲醇气相氧化羰基化工艺分离困难问题；50%以上的副产物CO2可转化为有用的有机产品，这可在一定程度上减少碳排放，实现节能减排的目的。 最后，从过程分析来看，甲醇氧化羰基化-酯交换耦合工艺具有一定的优势，但从工业化实现来看，还需在催化剂的选择、制备以及工艺参数方面开展细致深入的研究。

Dimethyl carbonate is an excellent performance and green environmental protection of organic chemicals, is a transformation of the greenhouse gas CO2 potentially effective way. In recent years, more and more experts and scholars pay attention on its synthesis and application. Firstly, we carried out the thermodynamic analysis of different processes, the results showed: the synthesis of one step was not feasible, and the reaction path of the process was changed after adding the coupling agent, which made it possible in thermodynamics; after we compared the transesterification process with gas-phase oxidative carbonylation, we found that the epoxy chloropropane was better than epoxy propane in thermodynamically; gas-phase oxidative carbonylation is another method to the synthesis of DMC, we found that this method has much advantages after we did its thermodynamically analysis, under the high pressure and low temperature is favorable. Secondly, we used Aspen Plus software to do the simulation of these three methods. Analyzed the details of the process, and the result showed: transesterification process has much byproducts, the energy consumption was high, methanol gas-phase oxidative carbonylation has low conversion rate of methanol, the separation was difficult. On this basis, we proposed the new technology—coupling process, and we did the thermodynamic and simulation for it, we found: this method could enhance the conversation rate of CH3OH, the methanol conversion rate significantly improved, on the one hand，it can significantly reduced the methanol circulation, reduced cycle of energy consumption, to solve the problem of high energy consumption of the ester exchange process there, on the other hand, reduced the methanol/DMC separation difficulty, simple separation can be used to separate the two general distillation; by-product H2O transformed completely, solvedgas phase oxidation difficult separation problems; more than 50% of the by-product CO2 can be transformed into useful organic products, this can reduced carbon emissions, to a certain extent, to achieve the purpose of energy saving. Finally, from the view of process analysis, the coupling process has many advantages, but from the perspective of the industrialization, we still need to carry out in-depth and meticulous research on the choice of catalyst, preparation and process parameters.