人工活性骨的内部微细结构建模是快速成形技术制造人工活性骨的一个重要环节。采用面向对象的方法，提出并实现了人工活性骨内部微细结构的建模方案：首先以矩形平面片为基本构造单元片，构造出内部微细结构的模型。其次，每个矩形平面片生成分形插值曲面片。最后，按STL数据格式转换模型数据，生成人工活性骨内部微细结构的STL模型。 在建模中，提出了矩形平面片生成分形插值曲面片的算法，完成了骨单位、浮克曼管的构造算法，并实现了根据不同区域对浮克曼管的分布、骨单位的大小、结构等特征进行灵活调控，以满足内部微细结构模型的要求。 在阐述骨组织的组成、结构和功能的基础上，分析了具有活性的人工骨其内部结构应具备的条件，提出了骨内部微细结构的简化方法，建立了人工骨内部微细结构的模型。该模型是一个多孔、多空隙的结构，有较大的表面积与孔体积。它不仅考虑了微孔的大小、分布，而且还考虑了微孔的形状、结构，比较充分地体现了骨内部微细结构的特点，从而在结构上保证了人工骨的生物活性。 以人工活性骨内部微细结构的建模为核心，利用Visual C++6.0，开发了OpenGL环境下的软件包。该软件包输出了 STL数据格式的模型数据，从而为人工骨的快速成形制造准备了数据。

Internal microstructure for artificial bioactive bone is the important step to fabricating bioactive bone by rapid prototyping. A modeling of internal microstructure for artificial bioactive bone is presented and realized by an objected-oriented technology. The main steps as follows. Firstly, model of bone internal microstructure is constructed by basic structure unit(rectangular patch); Secondly, fractal interpolation surface patch is constructed by processing rectangular patch; thirdly, STL model of bone internal microstructure is formed by transforming model data according to STL formation. The algorithm of construction of a fractal interpolation surface patch based on rectangular patch is presented in the modeling, the construction algorithms of osteons and Volkmann canals are designed, and the distribution of Volkmann canals, the size and structure of osteons can be regulated and controlled according to different area, so it can satisfy the needs of the internal microstructure model. Based on a discussion about the composition, microstructure and role of bone tissue, the requirements that artificial bioactive bone should meet are discussed, a simplified method of bone microstructure is put forward, an internal microstructure model for artificial bioactive bone is established. The model is a structure with multi-holes, large area and volume. Not only the size and distribution but also the shape and structure of micro-holes are considered. The model is fundamentally similar in structure characters of bone tissue, so assuring the bioactivity of bone in structure. With the modeling of internal microstructure for artificial bioactive bone as the corn, a software package is developed with Visual C++ and OpenGL platform. It can output model data in STL formation, so completing the preparation for the data processing of fabricating artificial bone by rapid prototyping technology.